Assessing exchangeability in indirect and mixed treatment comparisons
نویسندگان
چکیده
منابع مشابه
Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons
BACKGROUND Indirect treatment comparison (ITC) and mixed treatment comparisons (MTC) have been increasingly used in network meta-analyses. This simulation study comprehensively investigated statistical properties and performances of commonly used ITC and MTC methods, including simple ITC (the Bucher method), frequentist and Bayesian MTC methods. METHODS A simple network of three sets of two-a...
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15 صفحه اولIdentifiability and exchangeability for direct and indirect effects.
We consider the problem of separating the direct effects of an exposure from effects relayed through an intermediate variable (indirect effects). We show that adjustment for the intermediate variable, which is the most common method of estimating direct effects, can be biased. We also show that even in a randomized crossover trial of exposure, direct and indirect effects cannot be separated wit...
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, ensayos clı́nicos con un fármaco en común? Rev Esp Cardiol. 2012, http:// dx.doi.org/10.1016/j.recesp.2012.06.024 2. Steiner S, Moertl D, Chen L, Coyle D, Wells GA. Network meta-analysis of prasugrel, ticagrelor, highand standard-dose clopidogrel in patients scheduled for percutaneous coronary interventions. Thromb Haemost. 2012;108:318–27. 3. Catalá-López F, Tobı́as A. Sı́ntesis de la evidencia...
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ژورنال
عنوان ژورنال: Comparative Effectiveness Research
سال: 2011
ISSN: 1179-8483
DOI: 10.2147/cer.s21307